Thermo Fisher Scientific Myeloperoxidase Polyclonal Antibody
Rabbit polyclonal antibody targeting human Myeloperoxidase (MPO). Validated for WB, IHC, and IP applications. Supplied as unconjugated liquid form at 1 mg/mL. Suitable for research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 0.5–2 µL/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human Myeloperoxidase (MPO) fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C for short term. For long term storage, keep at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866936 |
Target Information
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is initially produced as a single-chain precursor and subsequently cleaved into light and heavy chains. The mature MPO forms a tetramer composed of two light chains and two heavy chains. This enzyme generates hypohalous acids critical for the microbicidal activity of neutrophils. MPO is associated with disorders such as Myeloperoxidase Deficiency and Familial Alzheimer’s Disease (Type 1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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