Thermo Fisher Scientific ELOVL1 Polyclonal Antibody
Thermo Fisher Scientific의 ELOVL1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 ELOVL1 단백질을 검출하는 고품질 항체입니다. Western blot, IHC, ICC/IF에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ELOVL1 (Accession Q9BW60), corresponding to amino acid residues V108–I158 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818226 |
Product Specific Information
Antibody detects endogenous levels of total ELOVL1.
Target Information
Elongation of very long chain fatty acid-like (ELOVL) proteins 1–6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids.
ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER).
ELOVL1, also known as Ssc1, is the human homolog of the yeast ELO3 protein. It is highly expressed in stomach, skin, intestine, kidney, and lung.
ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids up to 26 carbons and may be required for epithelial cell and skin barrier development.
It is also important for myelin formation in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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