Thermo Fisher Scientific IFNAR2 Polyclonal Antibody
IFNAR2 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 적합하며, 인간, 마우스, 랫트 시료에 반응. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IFNAR2 (Accession P48551), corresponding to amino acid residues E438–G488 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850339 |
Product Specific Information
Antibody detects endogenous levels of total IFNAR2.
Target Information
The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins induced by viruses or double-stranded RNA. They confer an antiviral state in cells and compete for binding to a common cell surface receptor. Immune IFN (IFN-gamma) binds to a distinct receptor, IFN-alphaR, which is weakly responsive to type I interferons. In contrast, IFN-alpha/betaR binds and responds effectively to IFN-beta and several IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, IFN-alpha/betaR1 and IFN-alpha/betaR2, both involved in signal transduction and ligand binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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