Thermo Fisher Scientific PIM2 Monoclonal Antibody (OTI9A5), TrueMAB
인간 PIM2 단백질을 인식하는 마우스 단클론 항체로, 다양한 면역실험(WB, IHC, ICC, Flow, IP)에 적용 가능. 고순도 친화 크로마토그래피 정제 제품으로 안정적인 액상 형태. 연구용으로 암 관련 PIM2 단백질 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9A5 |
| Immunogen | Full length human recombinant PIM2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.87 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PIM2 is a proto-oncogene that phosphorylates BAD, partially inhibiting its apoptotic function. PIM proteins (PIM-1, PIM-2, and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 shares high homology with PIM-1 and exhibits similar oncogenic functions. It is abundantly expressed in hematopoietic tissues, spleen, thymus, peripheral blood leukocytes, testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion, and elevated levels have been observed in certain cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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