Thermo Fisher Scientific CK2 alpha-1 Polyclonal Antibody
Rabbit polyclonal antibody targeting CK2 alpha-1 (CSNK2A1), validated for WB, IHC, and ICC/IF. High specificity for human with predicted cross-reactivity in multiple species. Supplied unconjugated in liquid form, purified by antigen affinity chromatogr...
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Thermo Fisher Scientific CK2 alpha-1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–350 of Human CKII alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546661 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (91%), Chicken (96%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain catalytic activity, while the beta subunits undergo autophosphorylation. CK2 alpha-1 represents the alpha subunit and is located on chromosome 20, with a related pseudogene on chromosome 11. Three transcript variants encoding two different proteins have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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