Thermo Fisher Scientific GKAP1 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human GKAP1, validated for WB, IHC(P), and ICC/IF applications. High specificity and purity via antigen affinity chromatography. Supplied as liquid form in PBS with glycerol, suitable for research use only.
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Thermo Fisher Scientific GKAP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GKAP1. Recombinant protein control fragment (Product #RP-95674). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642017 |
Product Specific Information
Immunogen sequence:
KNHQGKDRPL TVSLKDFHSE DHISKKTEEL SSSQTLSHDG GFFNRLEDDV HKILIREKRR EQLTEYNGTD NCTAHEHNQA LVLKDG
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 85%
Target Information
The approximately 142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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