Thermo Fisher Scientific KCTD13 Monoclonal Antibody (OTI3B12)
인체 KCTD13 단백질을 인식하는 Thermo Fisher Scientific의 마우스 단클론 항체입니다. Western blot 및 IHC(P)에서 사용 가능하며, 고순도 친화 크로마토그래피 정제 제품입니다. 액상 형태로 제공되며, 안정적인 저장 및 운송 조건을 갖추고 있습니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific KCTD13 Monoclonal Antibody (OTI3B12)
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B12 |
| Immunogen | Full length human recombinant protein of KCTD13 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723305 |
Target Information
Cytochrome P450 super family proteins are monooxygenases that catalyze multiple biochemical reactions involved in drug metabolism and synthesis of cholesterol, steroids, and lipids.
CYP4F3, a 60 kDa protein, is a novel member of this family. It contains a conserved heme-binding domain near the C-terminus and catalyzes the ω-hydroxylation of LTB4.
CYP4F3 is localized in the endoplasmic reticulum and plays a vital role in the inactivation of LTB4 and controlling inflammation.
CYP4F3 exists in two functionally distinct isoforms:
- CYP4F3A, a neutrophil isoform, expressed in neutrophils and myeloid cells, catalyzes microsomal ω-hydroxylation of LTB4.
- CYP4F3B, a liver isoform, catalyzes conversion of arachidonic acid to 20-HETE, a potent activator of PKC.
These isoforms are implicated in cell proliferation, vascular tone, and natriuresis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.