
Thermo Fisher Scientific GPR1 Polyclonal Antibody
Thermo Fisher Scientific의 GPR1 Polyclonal Antibody는 인간 GPR1 단백질을 인식하는 rabbit polyclonal 항체로, IHC(P) 및 ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.1% sodium azide를 포함합니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 40 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human GPR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550249 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon, Monkey (100%)
- Marmoset, Bovine, Bat, Elephant, Pig (94%)
- Dog, Horse, Platypus (88%)
- Panda (81%)
- For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600–1,000 members and is the largest known class of molecular targets with proven therapeutic value.
GPR1 is an orphan receptor for the inflammation-associated leukocyte chemoattractant chemerin, suggesting a role for this receptor in the regulation of inflammation.
In yeast, G protein-coupled receptor 1 senses glucose and controls filamentous growth. It acts upstream of adenylate cyclase and is required for glucose activation of cAMP synthesis in concert with a glucose phosphorylation-dependent mechanism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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