Thermo Fisher Scientific BAG3 Polyclonal Antibody
BAG3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ELISA에 사용 가능하며 Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, 1.76 mg/mL 농도, 안정적인 PBS/glycerol buffer 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 380–575 of human BAG3 (NP_004272.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.76 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913878 |
Product Specific Information
Positive test controls include: A-549, HeLa, HepG2, Mouse brain, Mouse testis.
Immunogen sequence:
PSAVPSSPKS VATEERAAPS TAPAEATPPK PGEAEAPPKH PGVLKVEAIL EKVQGLEQAV DNFEGKKTDK KYLMIEEYLT KELLALDSVD PEGRADVRQA RRDGVRKVQT ILEKLEQKAI DVPGQVQVYE LQPSNLEADQ PLQAIMEMGA VAADKGKKNA GNAEDPHTET QQPEATAAAT SNPSSMTDTP GNPAAP
Target Information
BAG3 belongs to the BAG protein family that competes with Hip for binding to the Hsc70/Hsp70 ATPase domain and promotes substrate release. All BAG proteins possess an approximately 45-amino acid BAG domain near the C terminus but differ in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells, binding with high affinity and inhibiting chaperone activity in a Hip-repressible manner.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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