Thermo Fisher Scientific NDUFS2 Recombinant Rabbit Monoclonal Antibody (JE65-29)
NDUFS2 단백질을 인식하는 토끼 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, Protein A로 정제되었습니다. 인간, 생쥐, 랫트 시료에 반응하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE65-29 |
| Immunogen | Recombinant protein within human NDUFS2 aa 264–463/463 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2931187 |
Target Information
The protein encoded by the NDUFS2 gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Mammalian mitochondrial complex I consists of at least 43 subunits, seven encoded by mitochondrial DNA and the remainder by nuclear genes. The iron-sulfur protein fraction of complex I includes seven subunits, among them the NDUFS2 gene product. Complex I catalyzes NADH oxidation coupled with ubiquinone reduction and proton translocation across the mitochondrial membrane. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternative splicing results in multiple isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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