Thermo Fisher Scientific SLC1A2 Monoclonal Antibody (4G8)
SLC1A2 단백질을 표적으로 하는 Thermo Fisher Scientific의 단일클론 항체(4G8). 인간 시료에 반응하며 Western blot과 ELISA에 적합. 고순도 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G8 |
| Immunogen | SLC1A2 (NP_004162, 160–239 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
DEVSSLDAFL DLIRNLFPEN LVQACFQQIQ TVTKKVLVAP PPDEEANATS AVVSLLNETV TEVPEETKMV IKKGLEFKDGTarget Information
Excitatory amino acid transporter 2 (EAAT2) is a member of the solute transporter protein family.
This membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system.
Glutamate clearance is essential for proper synaptic activation and prevention of neuronal damage from excessive activation of glutamate receptors.
Mutations and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS).
Alternatively spliced transcript variants of this gene have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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