Thermo Fisher Scientific Phospho-RET (Tyr1096) Polyclonal Antibody
RET 단백질의 Tyr1096 인산화 형태를 특이적으로 검출하는 polyclonal antibody. Western blot에 최적화되어 있으며 인간, 생쥐, 랫드 시료에 반응. 고순도 affinity chromatography 정제, 액상 형태로 안정적 보관 가능.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Ret (Phospho-Tyr1096) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2661989 |
Product Specific Information
Phospho-RET (Tyr1096) Polyclonal Antibody detects endogenous levels of RET only when phosphorylated at Tyr1096.
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia type IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described but their biological validity has not been confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-64512_RET_P07949-1_Rabbit.svg, PA5-64512_RET_P07949-1_Rabbit_PDP.jpeg)
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