Thermo Fisher Scientific SRPX2 Polyclonal Antibody
SRPX2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 및 다양한 종에서 반응합니다. IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- PA533059
- 판매단위
- pk
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Thermo Fisher Scientific SRPX2 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 15–20 µg/mL
Publications: - (참조 없음)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Human, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 13 amino acid peptide from C-Terminus of human SRPX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550520 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Orangutan, Monkey, Bat, Rabbit (100%)
Galago, Marmoset, Elephant, Panda, Dog, Horse, Pig (92%)
Target Information
Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain. Mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation, and cognitive disorders.
SRPX2 acts as a novel mediator of angiogenesis and ligand for urokinase-type plasminogen activator, facilitating invasive migration of endothelial cells. It is overexpressed in gastric cancer, enhancing phosphorylation of focal adhesion kinase and promoting cellular migration and adhesion.
Therefore, SRPX2 may serve as a potential target for metastatic cancer treatment.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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