Thermo Fisher Scientific OTUB1 Monoclonal Antibody (OTI1E3), Biotin, TrueMAB
인간 OTUB1 단백질을 인식하는 mouse IgG1 단일클론 항체로, Biotin 결합 형태 제공. ELISA 및 Luminex 분석에 적합하며, 고순도 친화 크로마토그래피 정제. 안정적 PBS/BSA/glycerol 저장 buffer 구성으로 연구용에 최적.
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Thermo Fisher Scientific OTUB1 Monoclonal Antibody (OTI1E3), Biotin, TrueMAB
Applications and Tested Dilution
- ELISA (ELISA): 1:250–1:1,000
- Luminex (LUM): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Full length human recombinant OTUB1 protein produced in HEK293T cells |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
The OTUB1 gene encodes a member of the OTU superfamily of predicted cysteine proteases. The protein acts as a specific ubiquitin iso-peptidase, cleaving ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with other ubiquitin proteases and E3 ligases that regulate cytokine gene transcription in the immune system. OTUB1 is proposed to function in specific ubiquitin-dependent pathways, potentially providing an editing function for polyubiquitin chain growth. Alternative splicing generates multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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