Thermo Fisher Scientific DCLK1 Monoclonal Antibody (C9)
DCLK1 단백질을 인식하는 Mouse monoclonal antibody (Clone C9). Western blot 및 IHC(P) 실험에 적합하며, Human, Pig, Rat 시료에 반응. Protein A/G 정제, 1 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C9 |
| Immunogen | Recombinant Human DCLK1 protein (Tyr390–Val647, Accession #O15075) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093401 |
Target Information
DCAMKL1 (DCLK1), also known as doublecortin-like kinase 1, is a serine/threonine kinase containing two N-terminal doublecortin domains that bind microtubules and regulate their polymerization. It also has a C-terminal serine/threonine protein kinase domain homologous to Ca²⁺/calmodulin-dependent protein kinase, and a serine/proline-rich domain mediating multiple protein-protein interactions.
DCLK1 functions as a microtubule-associated kinase capable of autophosphorylation, with microtubule-polymerizing activity independent of its kinase function. It plays roles in neuronal migration, retrograde transport, neuronal apoptosis, and neurogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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