Thermo Fisher Scientific GTF2A2 Polyclonal Antibody
Rabbit에서 생성된 GTF2A2 폴리클로날 항체로 Western blot에 적합합니다. 인간 GTF2A2 유래 합성 펩타이드로 면역원 제작. Mouse 및 Rat 시료에서도 반응 예측. 액상 형태로 제공되며, -20°C에 보관. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human GTF2A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2691715 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972).
The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, which interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID.
TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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