Thermo Fisher Scientific ORC3 Polyclonal Antibody
Rabbit polyclonal antibody against ORC3 for WB, IHC, and IP applications. Recognizes human Origin Recognition Complex subunit 3-like region (aa 325–375). Supplied as liquid, 0.2 mg/mL, stored at 4°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 325 and 375 of human Origin Recognition Complex, Subunit 3-like |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
Histone deacetylase 2 (HDAC2), also known as transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 gene. In humans, HDAC2 is likely involved in regulating chromatin structure during transcription and associates with YY1, a zinc-finger transcription factor that negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This mechanism is conserved from yeast to humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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