Thermo Fisher Scientific RNF144B Monoclonal Antibody (OTI11G1), TrueMAB
인간 RNF144B 단백질을 인식하는 Mouse IgG1 단일클론 항체입니다. ICC/IF 및 Flow Cytometry에 사용 가능하며, 액상 형태로 1 mg/mL 농도로 제공됩니다. Affinity chromatography로 정제되었으며, -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–256 of human RNF144B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
E3 ubiquitin-protein ligase that accepts ubiquitin from E2 ubiquitin-conjugating enzymes (UBE2L3 and UBE2L6) in the form of a thioester and transfers the ubiquitin to targeted substrates such as LCMT2, promoting their degradation. It induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. Overexpression decreases the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection from cell death, although it is not inherently anti-apoptotic.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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