Thermo Fisher Scientific Lambda light chain Polyclonal Antibody
사람 유래 Lambda light chain을 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 비결합형 액상 포맷으로 제공. Affinity chromatography로 정제되어 높은 특이성과 재현성을 보장. 연구용으로 다양한 종에 교차 반응성 확인됨.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human IGLC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689512 |
Product Specific Information
This target displays homology in the following species:
Cow: 79%; Dog: 100%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 91%; Rat: 85%
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa).
Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region.
The ratio of kappa to lambda is 70:30.
Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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