Thermo Fisher Scientific Human Beclin 1 Synthetic Peptide
인간 Beclin-1 단백질의 C-말단 16개 아미노산 서열 기반 합성 펩타이드. PA5-20171 항체의 블로킹 펩타이드로 사용 가능. 자가포식 연구 및 단백질 상호작용 분석에 적합. PBS 완충액에 0.1% BSA 포함, -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human Beclin-1.
PEP-0288 can be used as a blocking peptide with polyclonal antibody PA5-20171.
Target Information
Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate.
Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways:
- PI3KC3-C1 is involved in the initiation of autophagosomes.
- PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis.
Beclin 1 also plays a role in antiviral host defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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