Thermo Fisher Scientific PCDHGB5 Polyclonal Antibody
인간 PCDHGB5 단백질을 인식하는 토끼 다클론 항체. 면역조직화학(IHC-P) 검증 완료. 액상 형태, 0.5 mg/mL 농도. 뇌 내 세포 간 결합 연구용으로 적합. 연구용으로만 사용 가능.
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Thermo Fisher Scientific PCDHGB5 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC-P)
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PCDHGB5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2688461 |
Target Information
The PCDHGB5 gene belongs to the protocadherin gamma gene cluster, which is one of three related clusters tandemly linked on chromosome 5. These clusters have an immunoglobulin-like organization, suggesting a novel mechanism in their regulation and expression.
The gamma cluster includes 22 genes divided into three subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes and 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region containing six cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins play critical roles in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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