Thermo Fisher Scientific HSD11B1 Polyclonal Antibody
HSD11B1 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체. Western blot에 적합하며 인간에 반응. 합성 펩타이드 면역원으로 제작됨. 액상 형태, 0.5 mg/mL 농도, -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (CTSYNMDRFINK) corresponding to the C-terminus amino acids of HSD11B1 (aa 283–292) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982889 |
Product Specific Information
- Predicted to react with bovine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. It can also catalyze the reverse reaction, converting cortisone to cortisol. Excess cortisol can lead to central obesity, and certain gene variations are associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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