Thermo Fisher Scientific SRP1 Polyclonal Antibody
Thermo Fisher Scientific의 SRP1 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western Blot과 IHC(P) 실험에 적합합니다. KLH 접합 합성 펩타이드 면역원으로 제작된 비결합형 항체로, 고순도 Protein A 정제 및 안정적인 액상 형태로 제공됩니다.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SRP1/karyopherin alpha 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The import of proteins into the nucleus involves at least two steps:
- Energy-independent docking of the protein to the nuclear envelope.
- Energy-dependent translocation through the nuclear pore complex.
Imported proteins require a nuclear localization sequence (NLS), typically consisting of short regions of basic amino acids or two such regions spaced approximately 10 amino acids apart. Proteins involved in the first step of nuclear import include Xenopus importin and its yeast homolog SRP1, which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins, as well as playing a role in VJ recombination.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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