Thermo Fisher Scientific TPSG1 Monoclonal Antibody (OTI1G1), TrueMAB
TPSG1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, Flow cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 인간 시료 반응성이 높으며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–283 of human TPSG1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tryptase gamma (TPSG1), also known as serine protease 31 or transmembrane tryptase, is an enzyme encoded by the TPSG1 gene in humans. Tryptases are trypsin-like serine proteases belonging to the peptidase family S1. They are enzymatically active only as heparin-stabilized tetramers and resistant to endogenous proteinase inhibitors.
Several tryptase genes are clustered on chromosome 16p13.3, with four functional genes identified: alpha I, beta I, beta II, and gamma I. Beta tryptases are mainly expressed in mast cells, whereas alpha-tryptases predominate in basophils. The TPSG1 gene differs from other family members by possessing a C-terminal hydrophobic domain that may serve as a membrane anchor. Tryptases are implicated as mediators in asthma and other allergic and inflammatory disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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