Thermo Fisher Scientific CaMKII beta Polyclonal Antibody

Thermo Fisher Scientific CaMKII beta Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 1.0 µg/mL
Publications: -

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 93%; Zebrafish: 100%

Target Information

CAMK2B (CaMKII beta) is a serine/threonine kinase involved in synaptic plasticity, synaptic vesicle mobilization, and regulation of gene expression. As a dominant kinase in the central nervous system, it may function in long-term potentiation and neurotransmitter release.
There are four CaMKII isozymes (alpha, beta, gamma, delta), which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca²⁺/CaM complex to the autoinhibitory domain of CaMKII. This process, known as Ca²⁺/CaM trapping, is thought to be involved in the synaptic encoding of information.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.