Thermo Fisher Scientific COMP Polyclonal Antibody
Rabbit polyclonal antibody against human COMP protein. Validated for Western Blot at 1 µg/mL. Predicted cross-reactivity with multiple species. Supplied as liquid, 0.9 mg/mL concentration. Recommended storage at 4°C short term or -20°C long term.
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Applications
Western Blot (WB)
- Tested dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 1–100 of Human COMP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11000733 |
Product Specific Information
- For Western Blot, this antibody shows non-specific bands at 65 kDa.
- Predicted to react with rat, horse, cow, dog, and chimpanzee based on sequence homology.
Target Information
COMP (Cartilage Oligomeric Matrix Protein) is a noncollagenous extracellular matrix protein composed of five identical glycoprotein subunits with EGF-like and calcium-binding (thrombospondin-like) domains.
Oligomerization occurs through formation of a five-stranded coiled coil and disulfide bonds.
Binding to other ECM proteins such as collagen depends on divalent cations.
Mutations in COMP can cause osteochondrodysplasias such as pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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