Thermo Fisher Scientific SPA17 Polyclonal Antibody
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Human SPA17 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로 세포 부착 및 면역세포 이동 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SPA17. Recombinant protein control fragment (Product #RP-97273). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647764 |
Product Specific Information
Immunogen sequence:
EQPDNIPAFA AAYFESLLEK REKTNFDPAE WGSKVEDRFY NNHAFEEQEP PEKSDPKQEE SQISGKEEET SVTILDSSEE DKEKEEVAAV K
Highest antigen sequence identity to the following orthologs:
- Mouse: 68%
- Rat: 67%
Target Information
This gene encodes a protein present at the cell surface.
- The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa).
- The C-terminus has an IQ calmodulin-binding motif.
- The central portion contains carbohydrate binding motifs and likely functions in cell-cell adhesion.
- Initially characterized by its involvement in sperm binding to the zona pellucida of the oocyte.
- Recent studies indicate roles in immune cell migration and metastasis.
- A retrotransposed pseudogene is present on chromosome 10q22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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