Thermo Fisher Scientific NR4A3 Monoclonal Antibody (1E9)
NR4A3 단백질을 표적으로 하는 마우스 단클론 항체(클론 1E9)로, Western blot, ICC/IF, ELISA에 적합합니다. 인간 반응성, 비결합형 액상 형태이며 PBS 버퍼에 보존됩니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific NR4A3 Monoclonal Antibody (1E9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E9 |
| Immunogen | NR4A3 (NP_008912, 414–521 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LDYSRYCPTD QAAAGTDAEH VQQFYNLLTA SIDVSRSWAE KIPGFTDLPK EDQTLLIESA FLELFVLRLS IRSNTAEDKF VFCNGLVLHR LQCLRGFGEW LDSIKDFS
Target Information
NOR-1, a NR4 nerve growth factor-like receptor, has been shown to affect neuronal development, T-cell apoptosis, and cancer development. NOR-1 binds to NBRE (NGFI-B response element) and regulates the pro-opiomelanocortin (POMC) gene. NOR-1 is induced rapidly but transiently by various stimuli. Downregulation of NOR-1 and other NGFI-B family members is correlated with drug addiction-prone behavior of Lewis rats.
Three human protein isoforms have been documented: NOR-1, NOR-1β, and NOR-1 3′ variant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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