Thermo Fisher Scientific NT5C3B Polyclonal Antibody
Human NT5C3B 단백질을 인식하는 Rabbit Polyclonal Antibody로 IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로 세포 내 m(7)GMP 관련 대사 연구에 적합.
- 카탈로그번호
- PA556558
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NT5C3B. Recombinant protein control fragment (Product #RP-93310) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644835 |
Product Specific Information
Immunogen sequence:
GKRCPSSYNI LDNSKIISEE CRKELTALLH HYYPIEIDPH RTVKEKLPHM VEWWTKAHNL LCQQKIQKFQ IAQVVRESNA MLREGYKTFF NTLYHNNIPL FIFSAGIGDI LEEI
Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 88%
Target Information
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684).
The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233).
Also has weak activity for CMP (PubMed:23223233, PubMed:24603684).
UMP and purine nucleotides are poor substrates (PubMed:23223233).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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