Thermo Fisher Scientific Caveolin 1 Monoclonal Antibody (Z034)
Caveolin-1 단백질을 인식하는 Mouse Monoclonal Antibody (Clone Z034). Western blot, ICC/IF, IP 등 다양한 응용에 적합. Human 등 여러 종에 반응하며, PBS buffer에 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2.0 µg/mL | View 6 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL | View 4 publications |
| Flow Cytometry (Flow) | – | View 1 publication |
| Immunoprecipitation (IP) | 2–5 µg/mL | View 2 publications |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Hamster, Human, Mouse, Non-human primate, Protozoa, Rabbit |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Z034 |
| Immunogen | Tyrosine-phosphorylated proteins from RSV-transformed chick embryo fibroblasts |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2532932 |
Target Information
Caveolin-1 (CAV1) is a scaffolding protein within caveolar membranes. It interacts directly with G-protein alpha subunits and regulates their activity. Caveolin-1 also contributes to co-stimulatory signaling essential for T-cell receptor (TCR)-mediated T-cell activation. It can bind to DPP4, inducing T-cell proliferation and NF-kappa-B activation in a TCR/CD3-dependent manner. Mutations in the CAV1 gene are associated with congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, and partial lipodystrophy/congenital cataracts with neurodegeneration syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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