
Thermo Fisher Scientific Mouse IL-6, Animal-Free Recombinant Protein, PeproTech
마우스 유래 IL-6 재조합 단백질로, 염증 및 B세포 성숙 관련 연구에 사용됩니다. E. coli 발현 시스템에서 생산되며, 순도 ≥98%, 엔도톡신 <0.1 EU/µg 수준입니다. 동결건조 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Functional Assay (Functional)
- Assay-dependent
View 1 publication
In vitro Assay (IV)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Mouse |
| Published species | Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT |
| Molecular Weight | 21.7 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | Stimulates proliferation of mouse B9 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.
This product is shipped at ambient temperature.
For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
IL-6 encodes a cytokine involved in inflammation and B cell maturation.
It acts as an endogenous pyrogen capable of inducing fever in autoimmune or infectious conditions.
IL-6 is primarily expressed at sites of acute and chronic inflammation, secreted into the serum, and mediates inflammatory responses through the interleukin 6 receptor alpha.
Elevated IL-6 levels are associated with various inflammatory diseases, including diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi sarcoma, and COVID-19 (SARS-CoV-2 infection).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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