Thermo Fisher Scientific Cytokeratin 6 Polyclonal Antibody
Cytokeratin 6 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 및 마우스 시료에 반응합니다. Western Blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 134–564 of Human Cytokeratin 6B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2546610 |
Product Specific Information
- Recommended positive control: HeLa cells
- Predicted reactivity: Mouse (89%), Bovine (91%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region, known as hyperproliferation-related keratins.
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and epidermis under normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is associated with differentiation.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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