Thermo Fisher Scientific TK1 Monoclonal Antibody (C301)
Human TK1 단백질을 인식하는 Mouse IgG2b 단클론 항체로 Western blot, IHC, ICC/IF에 적합. 고순도 Protein A/G 정제, 1 mg/mL 농도. PBS/glycerol 용액에 보관하며 연구용으로 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C301 |
| Immunogen | Recombinant Human TK1 protein, Ser2–Asn234 (Accession #P04183) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091161 |
Target Information
Thymidine Kinase 1 (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation of deoxythymidine to deoxythymidine 5'-phosphate, an essential step in DNA synthesis. TK1 is involved in the mechanism of antiviral drugs such as AZT and is used in hybridoma selection for monoclonal antibody production. Clinically, TK1 serves as a marker for cell proliferation, being expressed primarily during cell division.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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