Thermo Fisher Scientific Myotilin Polyclonal Antibody
Human Myotilin 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 근육 수축 관련 단백질 연구 및 근육 질환 연구용으로 적합합니다.
- 카탈로그번호
- PA558082
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Myotilin. Recombinant protein control fragment (Product # RP-102782) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644392 |
Product Specific Information
Immunogen sequence:
ACVAKNRAGE ATFTVQLDVL AKEHKRAPMF IYKPQSKKVL EGDSVKLECQ ISAIPPPKLF WKRNNEMVQF NTDRISLYQD NTGRVTLLIK DVNKKDAG
- Highest antigen sequence identity to orthologs:
- Mouse: 93%
- Rat: 95%
Target Information
This gene encodes a cytoskeletal protein that plays a significant role in maintaining the stability of thin filaments during muscle contraction. The protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly.
Mutations in this gene are associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants have been described, though some full-length forms remain undetermined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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