Thermo Fisher Scientific RAB27A Monoclonal Antibody (1G7)
RAB27A 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ELISA에 사용 가능. 인간 시료 반응성, PBS buffer에 보관. Affinity chromatography로 정제되며 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G7 |
| Immunogen | RAB27A (NP_004571, 122–221 a.a) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
YCENPDIVLC GNKSDLEDQR VVKEEEAIAL AEKYGIPYFE TSAANGTNIS QAIEMLLDLI MKRMERCVDK SWIPEGVVRS NGHASTDQLS EEKEKGACGC
Target Information
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family.
It is membrane-bound and may be involved in protein transport and small GTPase-mediated signal transduction.
Mutations in this gene are associated with Griscelli syndrome type 2.
Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Plays a role in cytotoxic granule exocytosis in lymphocytes and is required for both granule maturation and granule docking and priming at the immunologic synapse.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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