Thermo Fisher Scientific HLA-F Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1.0 µg/mL
• Publications: [참고문헌 링크]

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: Assay-Dependent
• Publications: [참고문헌 링크]

Product Specifications

Product Specific Information

This target displays homology in the following species:

• Cow: 93%
• Human: 100%
• Pig: 100%

Target Information

HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove and is thought to bind a restricted subset of peptides for immune presentation.

HLA and MHC antibodies play a significant role in immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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