Thermo Fisher Scientific TCAP Polyclonal Antibody
TCAP 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot과 ELISA에 적합합니다. 인간 시료 반응성이 있으며, 고순도 Affinity Chromatography 정제 및 액상 형태로 제공됩니다. 근육 단백질 연구 및 사코메어 조립 관련 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–167 of human TCAP (NP_003664.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.43 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806670 |
Product Specific Information
- Immunogen sequence:
MATSELSCEV SEENCERREA FWAEWKDLTL STRPEEGCSL HEEDTQRHET YHQQGQCQVL VQRSPWLMMR MGILGRGLQE YQLPYQRVLP LPIFTPAKMG ATKEEREDTP IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM SQEAQRG - Positive Samples: Mouse heart, Mouse skeletal muscle, Rat heart, Rat skeletal muscle
- Cellular Location: Cytoplasm, myofibril, sarcomere
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold for myofibrils and other muscle-related proteins.
TCAP is a protein found in striated and cardiac muscle that binds to titin Z1–Z2 domains and acts as a substrate of titin kinase, interactions critical to sarcomere assembly.
Mutations in the TCAP gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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