Thermo Fisher Scientific KLF17 Polyclonal Antibody
Rabbit polyclonal antibody for detection of human KLF17 protein. Suitable for IHC (paraffin) applications at 1:25–1:100 dilution. Detects endogenous KLF17 involved in transcriptional repression and EMT regulation. For research use only.
- 카탈로그번호
- PA550340
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific KLF17 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human Kruppel-like factor 17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635793 |
Product Specific Information
This antibody detects endogenous levels of total KLF17 protein.
Target Information
KLF17 is a transcriptional repressor that binds to promoter regions of target genes to inhibit their expression. It acts as a negative regulator of epithelial-mesenchymal transition (EMT) and metastasis, particularly in breast cancer. KLF17 specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator, repressing its expression. It may also function as a germ cell-specific transcription factor involved in spermatid differentiation and oocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.