Thermo Fisher Scientific HK3 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human Hexokinase III for WB, IHC, and ICC applications. Unconjugated liquid form with 1 mg/mL concentration. Provides high specificity and sensitivity for research use only.
- 판매단위
- pk
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Thermo Fisher Scientific HK3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 535–923 of Human Hexokinase III |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546142 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa
- Predicted reactivity: Mouse (90%), Rat (90%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Hexokinases phosphorylate glucose to produce glucose 6-phosphate, thus committing glucose to the glycolytic pathway. In vertebrates, there are four major glucose phosphorylating isoenzymes: hexokinase I, II, III, and IV (glucokinase).
Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product, glucose 6-phosphate. The catalytic activity of hexokinase III is associated with the C terminus, while regulatory function is associated with the N terminus.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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