Thermo Fisher Scientific TFPI Recombinant Rabbit Monoclonal Antibody (ARC1154)
Recombinant rabbit monoclonal antibody targeting human TFPI (amino acids 200–304). Validated for WB and ELISA applications. High purity via affinity chromatography. Supplied in PBS with glycerol and sodium azide. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1154 |
| Immunogen | Recombinant fusion protein containing amino acids 200–304 of human TFPI (UniProt ID: P10646) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849603 |
Product Specific Information
Immunogen sequence:
PQSTKVPSLF EFHGPSWCLT PADRGLCRAN ENRFYYNSVI GKCRPFKYSG CGGNENNFTS KQECLRACKK GFIQRISKGG LIKTKRKRKK QRVKIAYEEI FVKNM
Target Information
Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa–TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa–TF proteases in an autoregulatory loop.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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