Thermo Fisher Scientific PPAR delta Monoclonal Antibody (OTI4D10)
PPAR delta 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC/IF에 적합하며 인간 시료에 반응. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–244 of PPARD produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725077 |
Target Information
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and regulate peroxisome production in cells. These receptors are involved in various biological processes and may play roles in chronic diseases such as diabetes, obesity, atherosclerosis, and cancer. PPAR delta acts as an inhibitor of ligand-induced transcription activity of PPAR alpha and gamma, integrating transcription repression and nuclear receptor signaling. Elevated expression is observed in colorectal cancer cells and can be repressed by the tumor suppressor APC. Mouse knockout studies suggest roles in myelination, lipid metabolism, and epidermal cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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