Thermo Fisher Scientific AMZ2 Polyclonal Antibody
AMZ2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot에 적합. Rat 시료 반응성 확인됨. Affinity chromatography로 정제되었으며 PBS 기반 버퍼에 보관. 연구용 전용 제품으로 금속단백질 분해효소 연구에 유용.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of rat AMZ2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689724 |
Product Specific Information
This target displays homology in the following species:
Cow: 77%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 86%; Rat: 93%
Target Information
AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. It is also expressed in kidney, liver, pancreas, lung, brain, and placenta, as well as in fetal tissues such as kidney, liver, lung, and brain.
AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. It is inhibited by general metalloprotease inhibitors such as o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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