Thermo Fisher Scientific MERS Coronavirus Spike Protein S1 Monoclonal Antibody (23)

Thermo Fisher Scientific MERS Coronavirus Spike Protein S1 Monoclonal Antibody (Clone 23)

Applications

• ELISA

Tested Dilution: 1:1,000–1:2,000

Product Specifications

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for MERS-CoV (NCoV/Novel coronavirus) Spike Protein S1.

Target Information

The spike (S) glycoprotein of coronaviruses contains protrusions that bind to specific receptors on the host cell, essential for host specificity and viral infectivity.
The term peplomer refers to a grouping of heterologous proteins on the virus surface that function together.
The spike (S) glycoprotein mediates membrane fusion required for virus entry and cell fusion and is a major immunogen and target for entry inhibitors.
The S protein consists of two subunits:

• S1 subunit: contains a receptor-binding domain engaging with the host cell receptor (ACE2).
• S2 subunit: mediates fusion between viral and host cell membranes.

The S protein plays key roles in inducing neutralizing antibody and T-cell responses, contributing to protective immunity during infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.