Thermo Fisher Scientific MERS Coronavirus Spike Protein S1 Monoclonal Antibody (23)
MERS-CoV Spike Protein S1에 특이적인 Mouse Monoclonal Antibody로, ELISA 등 연구용에 적합. 단일클론형 IgG1 항체이며, Protein A로 정제된 액상 형태. 보존제가 없으며 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific MERS Coronavirus Spike Protein S1 Monoclonal Antibody (Clone 23)
Applications
- ELISA
Tested Dilution: 1:1,000–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 23 |
| Immunogen | Recombinant MERS-CoV (NCoV/Novel coronavirus) Spike Protein S1 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785774 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for MERS-CoV (NCoV/Novel coronavirus) Spike Protein S1.
Target Information
The spike (S) glycoprotein of coronaviruses contains protrusions that bind to specific receptors on the host cell, essential for host specificity and viral infectivity.
The term peplomer refers to a grouping of heterologous proteins on the virus surface that function together.
The spike (S) glycoprotein mediates membrane fusion required for virus entry and cell fusion and is a major immunogen and target for entry inhibitors.
The S protein consists of two subunits:
- S1 subunit: contains a receptor-binding domain engaging with the host cell receptor (ACE2).
- S2 subunit: mediates fusion between viral and host cell membranes.
The S protein plays key roles in inducing neutralizing antibody and T-cell responses, contributing to protective immunity during infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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