Thermo Fisher Scientific FGL2 Polyclonal Antibody
Human FGL2 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB 및 ELISA에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. -20°C 보관, 동결/해동 반복 피할 것. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 24–140 of human FGL2 (NP_006673.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.71 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805556 |
Product Specific Information
Immunogen sequence:
NNETEEIKDE RAKDVCPVRL ESRGKCEEAG ECPYQVSLPP LTIQLPKQFS RIEEVFKEVQ NLKEIVNSLK KSCQDCKLQA DDNGDPGRNG LLLPSTGAPG EVGDNRVREL ESEVNKL
Positive Samples: HepG2
Target Information
Fibrinogen-like protein 2 (FGL2), also known as fibroleukin, is secreted by T cells and is involved in diseases where thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome, and xenograft rejection.
Constitutively expressed in cytotoxic T cells, FGL2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation.
FGL2 is a serine protease that directly cleaves prothrombin to thrombin and functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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