Thermo Fisher Scientific OGDH Polyclonal Antibody
OGDH 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. WB, IHC, ICC 등 다양한 응용 가능. 고순도 Affinity chromatography 정제. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OGDH (Accession Q02218), corresponding to amino acid residues L50–S100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853983 |
Product Specific Information
Antibody detects endogenous levels of total OGDH.
Target Information
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex, which catalyzes the conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO₂ during the Krebs cycle.
The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor.
A congenital deficiency in 2-oxoglutarate dehydrogenase activity may lead to hypotonia, metabolic acidosis, and hyperlactatemia.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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