Thermo Fisher Scientific THAP1 Monoclonal Antibody (8D10C8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:200-1:1,000

-

Flow Cytometry (Flow)

1:200-1:400

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

8D10C8

Immunogen

Purified recombinant fragment of human THAP1 (AA: 1-213) expressed in E. coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:THAP1,uniProtId:Q9NVV9-1,ncbiNodeId:9606,antigenRange:1-213,antigenLength:213,antigenImageFileName:MA5-31931_THAP1_Q9NVV9-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31931_THAP1_Q9NVV9-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2787554

Product Specific Information

MA5-31931 has been tested in indirect ELISA.

Target Information

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5-\[AT\]NTNN\[GT\]GGCA\[AGT\]-3 core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.