Thermo Fisher Scientific BAMBI Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human BAMBI if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BAMBI,uniProtId:Q13145-1,ncbiNodeId:9606,antigenRange:180-260,antigenLength:260,antigenImageFileName:PA5-52755_BAMBI_Q13145-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52755_BAMBI_Q13145-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638465

Product Specific Information

Immunogen sequence: NKRLQDQRQQ MLSRLHYSFH GHHSKKGQVA KLDLECMVPV SGHENCCLTC DKMRQADLSN DKILSLVHWG MYSGHGKLEF V

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 98%.

Target Information

BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.