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Thermo Fisher Scientific Phospho-SMAD2/SMAD3 (Thr8) Polyclonal Antibody

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SMAD2/SMAD3 Thr8 인산화 상태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 및 IHC에 적합하며, 인간, 마우스, 랫트 시료에 반응. PBS/glycerol buffer에 보관하며 -20°C에서 안정적.

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마지막 업데이트 2025. 08. 05. 오전 09:17

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Thermo Fisher Scientific PA599378 Phospho-SMAD2/SMAD3 (Thr8) Polyclonal Antibody 100 ul pk판매 단위 pk ·

재고 확인 필요재고 확인 필요

618,800원VAT 포함 680,680원

재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Application	Tested Dilution	Publications
Western Blot (WB)	1:500–1:2,000	-
Immunohistochemistry (Paraffin) (IHC-P)	1:50–1:200	-
Immunohistochemistry (Frozen) (IHC-F)	-	View 1 publication

항목	내용
Species Reactivity	Human, Mouse, Rat
Published Species	Mouse
Host / Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	A synthesized peptide derived from human SMAD3 (Accession P84022), corresponding to amino acid residues around phosphorylated Thr8.
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Sequential chromatography
Storage Buffer	PBS, pH 7.4, with 50% glycerol
Contains	0.02% sodium azide
Storage Conditions	-20°C
Shipping Conditions	Wet ice
RRID	AB_2818311

This antibody detects endogenous levels of Smad2/3 only when phosphorylated at Threonine 8.

Smad proteins are mammalian homologs of the Drosophila mothers against decapentaplegic (Mad) and act as downstream effectors of TGFβ/BMP signaling.

Smad1 (Madr1, JV4-1) and Smad5: Effectors of BMP-2 and BMP-4.
Smad2 (Madr2, JV18-1) and Smad3: Involved in TGFβ and Activin-mediated growth modulation.
Smad4 (DPC4): Mediates activities through interactions with other Smad family members.
Smad6 and Smad7: Negatively regulate Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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