Thermo Fisher Scientific Phospho-DDX3 (Thr322) Polyclonal Antibody
Phospho-DDX3 (Thr322) 폴리클로날 항체로, 인산화된 DDX3 단백질의 Thr322 부위를 특이적으로 인식합니다. IHC(P) 및 ICC/IF에 적합하며, Rabbit IgG 기반의 액상 형태입니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human DDX3/DEAD-box Protein 3 around the phosphorylation site of Thr322 (V-A-TP-P-G) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555070 |
Target Information
The protein encoded by this gene is a member of the large DEAD-box protein family, defined by the conserved Asp-Glu-Ala-Asp (DEAD) motif and exhibiting ATP-dependent RNA helicase activity. This protein displays high RNA-independent ATPase activity, stimulated by both RNA and DNA. It functions in both the nucleus and cytoplasm — in the nucleus, it participates in transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export; in the cytoplasm, it is involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been linked to tumorigenesis. A paralog exists on the Y chromosome, and pseudogenes are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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