Thermo Fisher Scientific RASD2 Monoclonal Antibody (OTI1F7)
RASD2 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, Flow cytometry 등에 사용 가능. 인간 시료에 반응하며, 액상 형태로 1 mg/mL 농도 제공. 뇌 발달 및 종양 혈관 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F7 |
| Immunogen | Full length human recombinant protein of RASD2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723558 |
Target Information
Rhes (also known as tumor endothelial marker 2, TEM2) is a small GTP-binding protein predominantly expressed in the striatal region of the brain. It belongs to the RASD subfamily of Ras-related GTP-binding proteins and is thought to play a role in brain development and function. Mice lacking this gene show increased anxiety and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes upregulated in tumor endothelium. Tumor endothelial markers are significantly upregulated during angiogenesis and neoangiogenesis, crucial for solid tumor growth. TEMs localized on the cell surface and conserved across species are of particular interest for anti-angiogenic therapy development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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